Reactome | TRPC1 translocates calcium from the extracellular region to the cytosol

Schema > Reaction > Entries

TRPC1 translocates calcium from the extracellular region to the cytosol Show undefined attributes

catalystActivity	[CatalystActivity:10778798] monoatomic cation channel activity of STIM1:TRPC1 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10778800
displayName	TRPC1 translocates calcium from the extracellular region to the cytosol
eventOf	[Pathway:R-GGA-5578775] Ion homeostasis - Gallus gallus [Pathway:R-GGA-983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2089943] TRPC1 translocates calcium from the extracellular region to the cytosol - Homo sapiens
input	[SimpleEntity:R-ALL-74112] Ca2+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	TRPC1 translocates calcium from the extracellular region to the cytosol Calcium Influx via TRPC1
output	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol]
precedingEvent	[Reaction:R-GGA-2089927] STIM1 binds TRPC1 forming STIM1:TRPC1 complex - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2089943
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5578775] Ion homeostasis [Pathway:R-GGA-983695] Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
(inferredTo)	[Reaction:R-HSA-2089943] TRPC1 translocates calcium from the extracellular region to the cytosol

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