Reactome | p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-GGA-205177] PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane] - Gallus gallus [Complex:R-GGA-205201] Tyrosine kinases:p-KIT complex [plasma membrane] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-1433501] Interaction of other adapter proteins with p-KIT - Gallus gallus [Reaction:R-GGA-205262] Direct recruitment of PI3K to p-KIT - Gallus gallus [Reaction:R-GGA-205328] Interaction of other tyrosine kinases with p-KIT - Gallus gallus [Reaction:R-GGA-205306] Interaction of SHP1 and KIT - Gallus gallus [Reaction:R-GGA-1562640] LNK binds to p-KIT and inhibit downstream signaling - Gallus gallus [Reaction:R-GGA-205286] GRB2:SOS interacts with p-KIT - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10749974
displayName	p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-GGA-205207] phospho-p-7Y-KIT [plasma membrane] [Complex:R-GGA-1433307] sSCF dimer [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-205310] p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] - Homo sapiens
maxDepth	3
name	p-7Y-KIT:sSCF dimer:p-7Y-KIT
positivelyRegulates	[PositiveRegulation:10820577] Positive regulation by 'p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]'
producedByEvent	[Reaction:R-GGA-205289] Autophosphorylation of KIT - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-205310
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(regulator)	[PositiveRegulation:10820577] Positive regulation by 'p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]'
(input)	[Reaction:R-GGA-205328] Interaction of other tyrosine kinases with p-KIT [Reaction:R-GGA-1433501] Interaction of other adapter proteins with p-KIT [Reaction:R-GGA-205306] Interaction of SHP1 and KIT [Reaction:R-GGA-1562640] LNK binds to p-KIT and inhibit downstream signaling [Reaction:R-GGA-205286] GRB2:SOS interacts with p-KIT [Reaction:R-GGA-205262] Direct recruitment of PI3K to p-KIT
(hasComponent)	[Complex:R-GGA-205201] Tyrosine kinases:p-KIT complex [plasma membrane] [Complex:R-GGA-1433538] Adapter proteins:p-KIT complex [plasma membrane] [Complex:R-GGA-205181] PTPN6:p-c-Kit complex [plasma membrane] [Complex:R-GGA-1562562] LNK:p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] [Complex:R-GGA-205271] SFKs:p-KIT complex [plasma membrane] [Complex:R-GGA-205202] GRB2:SOS1:p-KIT complex [plasma membrane] [Complex:R-GGA-205177] PI3K:p-KIT:sSCF dimer:p-KIT [plasma membrane]
(output)	[Reaction:R-GGA-205289] Autophosphorylation of KIT
(inferredTo)	[Complex:R-HSA-205310] p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]

p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] Show undefined attributes

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