Reactome | Interaction of SHP1 and KIT

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region [Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10750033
displayName	Interaction of SHP1 and KIT
eventOf	[Pathway:R-GGA-1433559] Regulation of KIT signaling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-205306] Interaction of SHP1 and KIT - Homo sapiens
input	[Complex:R-GGA-205310] p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] [EntityWithAccessionedSequence:R-GGA-197938] PTPN6 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of SHP1 and KIT
output	[Complex:R-GGA-205181] PTPN6:p-c-Kit complex [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-205306
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-1433559] Regulation of KIT signaling
(inferredTo)	[Reaction:R-HSA-205306] Interaction of SHP1 and KIT

Cite Us!