Reactome | 2xENPP1 hydrolyzes FAD to FMN

Schema > Reaction > Entries

2xENPP1 hydrolyzes FAD to FMN Show undefined attributes

catalystActivity	[CatalystActivity:10746747] dinucleotide phosphatase activity of 2xENPP1 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10746749
displayName	2xENPP1 hydrolyzes FAD to FMN
eventOf	[Pathway:R-GGA-196843] Vitamin B2 (riboflavin) metabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-196929] FLAD1 phosphorylates FMN - Gallus gallus [Reaction:R-GGA-196950] 2xTRAP hydrolyzes FMN to RIB - Gallus gallus
inferredFrom	[Reaction:R-HSA-196955] 2xENPP1 hydrolyzes FAD to FMN - Homo sapiens
input	[SimpleEntity:R-ALL-29386] FAD [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	2xENPP1 hydrolyzes FAD to FMN FAD + H2O => AMP + FMN + 2 H(+) FAD can be hydrolyzed back to FMN
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [SimpleEntity:R-ALL-73524] FMN [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-GGA-196929] FLAD1 phosphorylates FMN - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-196955
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-196843] Vitamin B2 (riboflavin) metabolism
(inferredTo)	[Reaction:R-HSA-196955] 2xENPP1 hydrolyzes FAD to FMN
(precedingEvent)	[Reaction:R-GGA-196929] FLAD1 phosphorylates FMN [Reaction:R-GGA-196950] 2xTRAP hydrolyzes FMN to RIB

Cite Us!