Reactome | COASY phosphorylates DP-CoA

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COASY phosphorylates DP-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10746706] dephospho-CoA kinase activity of COASY [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10746708
displayName	COASY phosphorylates DP-CoA
eventOf	[Pathway:R-GGA-196783] Coenzyme A biosynthesis - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-9837333] SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP - Gallus gallus [Reaction:R-GGA-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix - Gallus gallus [Reaction:R-GGA-199202] Phosphopantetheine conjugation of the ACP domain of FAS - Gallus gallus
inferredFrom	[Reaction:R-HSA-196773] COASY phosphorylates DP-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-196778] DP-CoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	COASY phosphorylates DP-CoA 3'-dephospho-CoA + ATP => ADP + CoA + H(+) Phosphorylation of dephospho-CoA to produce CoA
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol]
precedingEvent	[Reaction:R-GGA-196754] COASY transfers an adenylyl group from ATP to PPANT - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-196773
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-196783] Coenzyme A biosynthesis
(precedingEvent)	[Reaction:R-GGA-9837333] SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP [Reaction:R-GGA-199216] SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix [Reaction:R-GGA-199202] Phosphopantetheine conjugation of the ACP domain of FAS
(inferredTo)	[Reaction:R-HSA-196773] COASY phosphorylates DP-CoA

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