Reactome | Beta-catenin phosphorylation cascade

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Beta-catenin phosphorylation cascade Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10826291
displayName	Beta-catenin phosphorylation cascade
eventOf	[Pathway:R-GGA-195253] Degradation of beta-catenin by the destruction complex - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-195318] Phosphorylation of beta-catenin at Ser45 by CK1 alpha - Gallus gallus [Reaction:R-GGA-195287] Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 - Gallus gallus [Reaction:R-GGA-195283] Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 - Gallus gallus [Reaction:R-GGA-195300] Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 - Gallus gallus
inferredFrom	[Pathway:R-HSA-196299] Beta-catenin phosphorylation cascade - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Beta-catenin phosphorylation cascade
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-196299
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-195253] Degradation of beta-catenin by the destruction complex
(inferredTo)	[Pathway:R-HSA-196299] Beta-catenin phosphorylation cascade

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