Reactome | B3GAT dimers transfer GlcA to tetrasaccharide linker

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B3GAT dimers transfer GlcA to tetrasaccharide linker Show undefined attributes

catalystActivity	[CatalystActivity:10775259] galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity of B3GAT dimers [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10775261
displayName	B3GAT dimers transfer GlcA to tetrasaccharide linker
eventOf	[Pathway:R-GGA-1971475] Glycosaminoglycan-protein linkage region biosynthesis - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-1971482] CSGALNACTs transfer GalNAc to CS linker glycan - Gallus gallus [Reaction:R-GGA-9941039] FAM20B phosphorylates Xyl moiety - Gallus gallus [Reaction:R-GGA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker - Gallus gallus
inferredFrom	[Reaction:R-HSA-1889955] B3GAT dimers transfer GlcA to tetrasaccharide linker - Homo sapiens
input	[DefinedSet:R-GGA-2064214] Gal-Gal-Xyl-proteins [Golgi lumen] [SimpleEntity:R-ALL-1889970] UDP-GlcA [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	B3GAT dimers transfer GlcA to tetrasaccharide linker A glucuronate moiety is the fourth addition to the tetrasaccharide linker
output	[DefinedSet:R-GGA-2064225] GlcA-Gal-Gal-Xyl-proteins [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-GGA-1889978] B3GALT6 transfers Gal to the tetrasaccharide linker - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-1889955
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1971475] Glycosaminoglycan-protein linkage region biosynthesis
(precedingEvent)	[Reaction:R-GGA-1971482] CSGALNACTs transfer GalNAc to CS linker glycan [Reaction:R-GGA-9941039] FAM20B phosphorylates Xyl moiety [Reaction:R-GGA-9953259] EXTL3 dimer transfers GlcNAc to the GAG linker
(inferredTo)	[Reaction:R-HSA-1889955] B3GAT dimers transfer GlcA to tetrasaccharide linker

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