Reactome | phospho-MAPKAPK2 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10758559] protein serine/threonine kinase activity of p-S272,T222,T334-MAPKAPK2 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-450241] p-p38 MAPK: p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3 [cytosol] - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10744963
displayName	phospho-MAPKAPK2 [cytosol]
endCoordinate	400
hasModifiedResidue	[ModifiedResidue:10744959] O-phospho-L-threonine at 222 (in Homo sapiens) [ModifiedResidue:10744960] O-phospho-L-serine at 272 (in Homo sapiens) [ModifiedResidue:10744961] O-phospho-L-threonine at 334 (in Homo sapiens)
inDisease	false
inferredFrom	[DefinedSet:R-HSA-187726] p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3 [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-187760] p-S272,T222,T334-MAPKAPK2 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-MAPKAPK2 p-S272,T222,T334-MAPKAPK2 F1NCY7
producedByEvent	[Reaction:R-GGA-187688] p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 - Gallus gallus
referenceEntity	[ReferenceGeneProduct:uniprot:F1NCY7] UniProt:F1NCY7
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49591] Gallus gallus
stId	R-GGA-187760
startCoordinate	1

(physicalEntity)	[CatalystActivity:10758559] protein serine/threonine kinase activity of p-S272,T222,T334-MAPKAPK2 [cytosol]
(output)	[Reaction:R-GGA-187688] p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3
(hasComponent)	[Complex:R-GGA-450241] p-p38 MAPK: p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3 [cytosol]
(inferredTo)	[DefinedSet:R-HSA-187726] p-S272,T222,T334-MAPKAPK2, p-S,2T-MAPKAPK3 [cytosol] [EntityWithAccessionedSequence:R-HSA-187760] p-S272,T222,T334-MAPKAPK2 [cytosol]

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