Reactome | Synthesis of pyrophosphates in the cytosol

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Synthesis of pyrophosphates in the cytosol Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10827361
displayName	Synthesis of pyrophosphates in the cytosol
eventOf	[Pathway:R-GGA-1483249] Inositol phosphate metabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258976] inositol phosphate metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-1855219] I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol - Gallus gallus [Reaction:R-GGA-1855162] I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol - Gallus gallus [Reaction:R-GGA-1855179] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol - Gallus gallus [Reaction:R-GGA-1855223] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol - Gallus gallus [Reaction:R-GGA-1855166] PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol - Gallus gallus [Reaction:R-GGA-1855193] 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol - Gallus gallus [Reaction:R-GGA-1855227] IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol - Gallus gallus [Reaction:R-GGA-1855198] 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol - Gallus gallus [Reaction:R-GGA-1855216] IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol - Gallus gallus [Reaction:R-GGA-2023971] 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol - Gallus gallus [Reaction:R-GGA-1855158] 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol - Gallus gallus [Reaction:R-GGA-1855182] 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol - Gallus gallus [Reaction:R-GGA-1855165] (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol - Gallus gallus [Reaction:R-GGA-1855194] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol - Gallus gallus [Reaction:R-GGA-2023973] (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol - Gallus gallus
inferredFrom	[Pathway:R-HSA-1855167] Synthesis of pyrophosphates in the cytosol - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of pyrophosphates in the cytosol
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-1855167
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1483249] Inositol phosphate metabolism
(inferredTo)	[Pathway:R-HSA-1855167] Synthesis of pyrophosphates in the cytosol

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