Reactome | GST dimers conjugate GSH with cytosolic substrates

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GST dimers conjugate GSH with cytosolic substrates Show undefined attributes

catalystActivity	[CatalystActivity:10743943] glutathione transferase activity of GST dimers [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10743945
displayName	GST dimers conjugate GSH with cytosolic substrates
eventOf	[Pathway:R-GGA-156590] Glutathione conjugation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-176054] GST dimers conjugate GSH with cytosolic substrates - Homo sapiens
input	[DefinedSet:R-ALL-176070] Electrophilic substrate [cytosol] [SimpleEntity:R-ALL-29450] GSH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GST dimers conjugate GSH with cytosolic substrates Glutathione conjugation of cytosolic substrates
output	[DefinedSet:R-ALL-176049] electrophilic substrate:SG [cytosol]
precedingEvent	[Reaction:R-GGA-174394] GSS:Mg2+ dimer synthesizes GSH - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-176054
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-156590] Glutathione conjugation
(inferredTo)	[Reaction:R-HSA-176054] GST dimers conjugate GSH with cytosolic substrates

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