Reactome | benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A

Schema > Reaction > Entries

benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A Show undefined attributes

catalystActivity	[CatalystActivity:10740979] glycine N-benzoyltransferase activity of GLYAT-like proteins [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10740981
displayName	benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A
eventOf	[Pathway:R-GGA-177135] Conjugation of benzoate with glycine - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-159566] benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A - Homo sapiens
input	[SimpleEntity:R-ALL-159447] BEZ-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-159549] Gly [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A Benzoyl-CoA forms an amide bond with glycine
output	[SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-159564] HIPA [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-159443] benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-159566
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-177135] Conjugation of benzoate with glycine
(inferredTo)	[Reaction:R-HSA-159566] benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A

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