Reactome | PE is hydrolyzed to 1-acyl LPE by PLA2[3]

Schema > Reaction > Entries

PE is hydrolyzed to 1-acyl LPE by PLA2[3] Show undefined attributes

catalystActivity	[CatalystActivity:10772386] A2-type glycerophospholipase activity of PLA2(6) [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10772427
displayName	PE is hydrolyzed to 1-acyl LPE by PLA2[3]
eventOf	[Pathway:R-GGA-1482839] Acyl chain remodelling of PE - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-1482667] 1-acyl LPE is acylated to PE by LPEAT - Gallus gallus
inferredFrom	[Reaction:R-HSA-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-1500581] PE [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PE is hydrolyzed to 1-acyl LPE by PLA2[3]
output	[SimpleEntity:R-ALL-1498738] 1-acyl LPE [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-GGA-1482667] 1-acyl LPE is acylated to PE by LPEAT - Gallus gallus [Reaction:R-GGA-1482646] 2-acyl LPE is acylated to PE by LPEAT - Gallus gallus [Reaction:R-GGA-1482962] CDP-ETA and DAG are converted to PE by CEPT1/EPT1 - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-1482887
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1482839] Acyl chain remodelling of PE
(precedingEvent)	[Reaction:R-GGA-1482667] 1-acyl LPE is acylated to PE by LPEAT
(inferredTo)	[Reaction:R-HSA-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3]