Reactome | CDC25A [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

catalystActivities	[CatalystActivity:10733065] phosphoprotein phosphatase activity of CDC25A [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-GGA-9943687] PLK3 phosphorylates CDC25A - Gallus gallus [Reaction:R-GGA-9942578] Phosphorylation of CDC25A by p38 MAPK - Gallus gallus [Reaction:R-GGA-69608] Phosphorylation of CDC25A by CHEK2 - Gallus gallus [Reaction:R-GGA-69604] Phosphorylation of CDC25A by CHEK1 - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10733064
displayName	CDC25A [nucleoplasm]
endCoordinate	524
inDisease	false
inferredFrom	[CandidateSet:R-HSA-187904] Cdc25 A/B [nucleoplasm] - Homo sapiens [DefinedSet:R-HSA-69261] CDC25 [nucleoplasm] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-143487] CDC25A [nucleoplasm] - Homo sapiens
maxDepth	1
name	CDC25A CDC25A A0A8V1A896
producedByEvent	[Reaction:R-GGA-170159] Translocation of Cdc25 to the nucleus - Gallus gallus
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8V1A896] UniProt:A0A8V1A896
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49591] Gallus gallus
stId	R-GGA-143487
startCoordinate	1

(input)	[Reaction:R-GGA-9943687] PLK3 phosphorylates CDC25A [Reaction:R-GGA-69608] Phosphorylation of CDC25A by CHEK2 [Reaction:R-GGA-9942578] Phosphorylation of CDC25A by p38 MAPK [Reaction:R-GGA-69604] Phosphorylation of CDC25A by CHEK1
(inferredTo)	[CandidateSet:R-HSA-187904] Cdc25 A/B [nucleoplasm] [DefinedSet:R-HSA-69261] CDC25 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-143487] CDC25A [nucleoplasm]
(physicalEntity)	[CatalystActivity:10733065] phosphoprotein phosphatase activity of CDC25A [nucleoplasm]
(output)	[Reaction:R-GGA-170159] Translocation of Cdc25 to the nucleus

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