Reactome | NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10770298] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10770169
displayName	NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane]
hasComponent	[Complex:R-GGA-1250191] NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] [EntityWithAccessionedSequence:R-GGA-74787] PIK3CA [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-1250508] NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] - Homo sapiens
maxDepth	7
memberOf	[DefinedSet:R-GGA-2316432] Activator:PI3K [plasma membrane] - Gallus gallus
name	NRG1/2:p-ERBB3:p-ERBB2:PI3K
producedByEvent	[Reaction:R-GGA-1250189] Binding of PI3K to ERBB2:p-ERBB3 heterodimer - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-1250508
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(physicalEntity)	[CatalystActivity:10770298] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane]
(output)	[Reaction:R-GGA-1250189] Binding of PI3K to ERBB2:p-ERBB3 heterodimer
(hasMember)	[DefinedSet:R-GGA-2316432] Activator:PI3K [plasma membrane]
(inferredTo)	[Complex:R-HSA-1250508] NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane]

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