Reactome | viral dsRNA:MDA5 [cytosol]

Schema > Complex > Entries

viral dsRNA:MDA5 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-1227703] dsRNA:MDA5:IPS1 [mitochondrial outer membrane] - Gallus gallus [Complex:R-GGA-1227807] dsRNA:MDA5:Atg5-Atg12:IPS1 [mitochondrial outer membrane] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-1227695] NLRC5 binds to CARD domain of Mda5 and prevents IPS1 binding - Gallus gallus [Reaction:R-GGA-1227709] Activated MDA5 binds IPS-1 - Gallus gallus [Reaction:R-GGA-1227804] Inhibition of MDA5-IPS1 signaling by Atg5-Atg12 conjugate - Gallus gallus
created	[InstanceEdit:1227707] Shamovsky, V, 2011-03-10
dbId	1227681
deleted	[Deleted:6791270] Deletion of instance: 1227680
displayName	viral dsRNA:MDA5 [cytosol]
hasComponent	[GenomeEncodedEntity:R-IBR-9014385] IBV dsRNA intermediate form [cytosol] 2 × [EntityWithAccessionedSequence:R-GGA-1227688] MDA5 [cytosol]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:9014372] Activation of the chicken type I interferon response by infectious bronchitis coronavirus
maxDepth	2
modified	[InstanceEdit:9014384] Shamovsky, Veronica, 2017-07-28
name	viral dsRNA:MDA5
producedByEvent	[Reaction:R-GGA-1227694] dsRNA binds to MDA5 - Gallus gallus
relatedSpecies	[Species:9014381] Infectious bronchitis virus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-1227681
updateTrackers	[UpdateTracker:9897671] Update Tracker - [Complex:1227681] viral dsRNA:MDA5 [cytosol] - v62:[addLiteratureReference, add_removeHasComponent, modifyName] [UpdateTracker:9892976] Update Tracker - [Complex:1227681] viral dsRNA:MDA5 [cytosol] - v54:[add_removeHasComponent]

Referrals

(updatedInstance)	[UpdateTracker:9897671] Update Tracker - [Complex:1227681] viral dsRNA:MDA5 [cytosol] - v62:[addLiteratureReference, add_removeHasComponent, modifyName] [UpdateTracker:9892976] Update Tracker - [Complex:1227681] viral dsRNA:MDA5 [cytosol] - v54:[add_removeHasComponent]
(replacementInstances)	[Deleted:6791270] Deletion of instance: 1227680
(hasComponent)	[Complex:R-GGA-1227807] dsRNA:MDA5:Atg5-Atg12:IPS1 [mitochondrial outer membrane] [Complex:R-GGA-1227703] dsRNA:MDA5:IPS1 [mitochondrial outer membrane]
(input)	[Reaction:R-GGA-1227804] Inhibition of MDA5-IPS1 signaling by Atg5-Atg12 conjugate [Reaction:R-GGA-1227695] NLRC5 binds to CARD domain of Mda5 and prevents IPS1 binding [Reaction:R-GGA-1227709] Activated MDA5 binds IPS-1
(output)	[Reaction:R-GGA-1227694] dsRNA binds to MDA5