Reactome | FNTA:FNTB transfers farnesyl to GBP1

Schema > Reaction > Entries

FNTA:FNTB transfers farnesyl to GBP1 Show undefined attributes

catalystActivity	[CatalystActivity:10604481] protein farnesyltransferase activity of FNTA:FNTB [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10646963
displayName	FNTA:FNTB transfers farnesyl to GBP1
eventOf	[Pathway:R-DRE-9953170] GBP-mediated host defense - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-9956706] GBP1 binds actin - Danio rerio [Reaction:R-DRE-9968553] GBP1 binds GTP - Danio rerio
inferredFrom	[Reaction:R-HSA-9948016] FNTA:FNTB transfers farnesyl to GBP1 - Homo sapiens
input	[SimpleEntity:R-ALL-2530486] FPP [cytosol] [DefinedSet:R-DRE-1031698-5] Homologues of GBP1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FNTA:FNTB transfers farnesyl to GBP1 Farnesyltransferase complex farnesylates GBP1 GBP1 prenylation
output	[DefinedSet:R-DRE-9947912-5] Homologues of S-farn-C589-GBP1 [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9948016
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9953170] GBP-mediated host defense
(precedingEvent)	[Reaction:R-DRE-9956706] GBP1 binds actin [Reaction:R-DRE-9968553] GBP1 binds GTP
(inferredTo)	[Reaction:R-HSA-9948016] FNTA:FNTB transfers farnesyl to GBP1

Cite Us!