Reactome | factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa

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factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10646233
displayName	factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa
eventOf	[Pathway:R-DRE-9769735] Initiation of coagulation cascade - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9933742] factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa - Homo sapiens
input	[Complex:R-DRE-9930795] factor Va intermediate [extracellular region] [Complex:R-DRE-140689] factor Xa [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa FVa intermediate + FXa -> FVa intermediate:FXa
output	[Complex:R-DRE-9930788] FVa intermediate:FXa [plasma membrane]
precedingEvent	[Reaction:R-DRE-9769737] factor V -> factor Va intermediate + factor V activation peptide (FXa catalyst) - Danio rerio [Reaction:R-DRE-9822512] TF:FVIIa:FXa ->TF:FVIIa + FXa - Danio rerio [Reaction:R-DRE-9930790] factor V -> factor Va intermediate + factor V activation peptide (thrombin catalyst) - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9933742
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9769735] Initiation of coagulation cascade
(inferredTo)	[Reaction:R-HSA-9933742] factor Va intermediate + factor Xa -> factor Va intermediate:factor Xa

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