Reactome | Epigenetic regulation of gene expression by MLL3 and MLL4 complexes

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650688
displayName	Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
eventOf	[Pathway:R-DRE-9917777] Epigenetic regulation by WDR5-containing histone modifying complexes - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-9851695] Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes - Danio rerio
inferredFrom	[Pathway:R-HSA-9818564] Epigenetic regulation of gene expression by MLL3 and MLL4 complexes - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-9818564
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9917777] Epigenetic regulation by WDR5-containing histone modifying complexes
(inferredTo)	[Pathway:R-HSA-9818564] Epigenetic regulation of gene expression by MLL3 and MLL4 complexes

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