Reactome | MCM2 binds MCM4:MCM6:MCM7 heterotrimer

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MCM2 binds MCM4:MCM6:MCM7 heterotrimer Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10641696
displayName	MCM2 binds MCM4:MCM6:MCM7 heterotrimer
eventOf	[Pathway:R-DRE-68867] Assembly of the pre-replicative complex - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-9749253] Formation of MCM2-7 complex - Danio rerio
inferredFrom	[Reaction:R-HSA-9757258] MCM2 binds MCM4:MCM6:MCM7 heterotrimer - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-68557] mcm2 [nucleoplasm] [Complex:R-DRE-69018] MCM4:MCM6:MCM7 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	MCM2 binds MCM4:MCM6:MCM7 heterotrimer
output	[Complex:R-DRE-9757255] MCM2:MCM4:MCM6:MCM7 [nucleoplasm]
precedingEvent	[Reaction:R-DRE-9757257] MCM4, MCM6 and MCM7 form a heterotrimer - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9757258
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-68867] Assembly of the pre-replicative complex
(precedingEvent)	[Reaction:R-DRE-9749253] Formation of MCM2-7 complex
(inferredTo)	[Reaction:R-HSA-9757258] MCM2 binds MCM4:MCM6:MCM7 heterotrimer

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