Reactome | ADA deamidates RBV

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10563908] deaminase activity of ADA [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10641601
displayName	ADA deamidates RBV
eventOf	[Pathway:R-DRE-9755088] Ribavirin ADME - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9754964] ADA deamidates RBV - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [ChemicalDrug:R-ALL-9680963] RBV [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ADA deamidates RBV
output	[SimpleEntity:R-ALL-31633] NH4+ [cytosol] [SimpleEntity:R-ALL-9755025] RBV-COOH [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9754964
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9755088] Ribavirin ADME
(inferredTo)	[Reaction:R-HSA-9754964] ADA deamidates RBV

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