Reactome | PGRMC2:Hemes translocate to the nucleus

Schema > BlackBoxEvent > Entries

PGRMC2:Hemes translocate to the nucleus Show undefined attributes

category	omitted
compartment	[Compartment:13231] nuclear envelope [Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10640792
displayName	PGRMC2:Hemes translocate to the nucleus
eventOf	[Pathway:R-DRE-9707616] Heme signaling - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-DRE-9707856] PGRMC2:Hemes dissociates - Danio rerio [Reaction:R-DRE-9707523] Hemes bind to BACH1:MAFK - Danio rerio
inferredFrom	[BlackBoxEvent:R-HSA-9707606] PGRMC2:Hemes translocate to the nucleus - Homo sapiens
input	[Complex:R-DRE-9707603] PGRMC2:Hemes [nuclear envelope]
isInDisease	false
isInferred	true
maxDepth	1
name	PGRMC2:Hemes translocate to the nucleus
output	[Complex:R-DRE-9707849] PGRMC2:Hemes [nucleoplasm]
precedingEvent	[Reaction:R-DRE-9707683] PGRMC2 binds Hemes - Danio rerio
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68323] Danio rerio
stId	R-DRE-9707606
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9707616] Heme signaling
(precedingEvent)	[BlackBoxEvent:R-DRE-9707856] PGRMC2:Hemes dissociates [Reaction:R-DRE-9707523] Hemes bind to BACH1:MAFK
(inferredTo)	[BlackBoxEvent:R-HSA-9707606] PGRMC2:Hemes translocate to the nucleus

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