Reactome | CYP19A1 binds Aromatase inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10640762
displayName	CYP19A1 binds Aromatase inhibitors
eventOf	[Pathway:R-DRE-193144] Estrogen biosynthesis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9707353] CYP19A1 binds Aromatase inhibitors - Homo sapiens
input	[DefinedSet:R-ALL-9707314] Aromatase inhibitors [cytosol] [EntityWithAccessionedSequence:R-DRE-193137] CYP19A1 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CYP19A1 binds Aromatase inhibitors
output	[Complex:R-DRE-9707321] CYP19A1:Aromatase inhibitors [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9707353
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-193144] Estrogen biosynthesis
(inferredTo)	[Reaction:R-HSA-9707353] CYP19A1 binds Aromatase inhibitors

Cite Us!