Reactome | RB1 translocates to the nucleus

Schema > BlackBoxEvent > Entries

RB1 translocates to the nucleus Show undefined attributes

category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10640011
displayName	RB1 translocates to the nucleus
eventOf	[Pathway:R-DRE-69231] Cyclin D associated events in G1 - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-9018017] RB1 binds and inhibits E2F1/2/3:DP1/2 complexes - Danio rerio [Reaction:R-DRE-69227] Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes - Danio rerio
inferredFrom	[BlackBoxEvent:R-HSA-9659820] RB1 translocates to the nucleus - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-9660621] rb1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	RB1 translocates to the nucleus
output	[EntityWithAccessionedSequence:R-DRE-68642] rb1 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68323] Danio rerio
stId	R-DRE-9659820
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-69231] Cyclin D associated events in G1
(precedingEvent)	[Reaction:R-DRE-9018017] RB1 binds and inhibits E2F1/2/3:DP1/2 complexes [Reaction:R-DRE-69227] Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes
(inferredTo)	[BlackBoxEvent:R-HSA-9659820] RB1 translocates to the nucleus