Reactome | p-S10 CDKN1B translocates to the cytosol

Schema > BlackBoxEvent > Entries

p-S10 CDKN1B translocates to the cytosol Show undefined attributes

category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:459] cytoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10639388
displayName	p-S10 CDKN1B translocates to the cytosol
eventOf	[Pathway:R-DRE-9634638] Estrogen-dependent nuclear events downstream of ESR-membrane signaling - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9632873] p-S10 CDKN1B translocates to the cytosol - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-9632832] phospho-cdkn1ba [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	p-S10 CDKN1B translocates to the cytosol
output	[EntityWithAccessionedSequence:R-DRE-9632829] phospho-cdkn1ba [cytosol]
precedingEvent	[Reaction:R-DRE-9632868] CDKN1B is phosphorylated in response to estrogen - Danio rerio
regulatedBy	[Requirement:10617700] Requirement by 'XPO1 [nucleoplasm]' [PositiveRegulation:10639389] Positive regulation by 'p-Y185,Y187 MAPK1 dimer [nucleoplasm]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68323] Danio rerio
stId	R-DRE-9632873
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9634638] Estrogen-dependent nuclear events downstream of ESR-membrane signaling
(inferredTo)	[BlackBoxEvent:R-HSA-9632873] p-S10 CDKN1B translocates to the cytosol

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