Reactome | Regulation of localization of FOXO transcription factors

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Regulation of localization of FOXO transcription factors Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648672
displayName	Regulation of localization of FOXO transcription factors
eventOf	[Pathway:R-DRE-9614085] FOXO-mediated transcription - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-199299] AKT phosphorylates FOXO transcription factors - Danio rerio [BlackBoxEvent:R-DRE-9614414] AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol - Danio rerio [Reaction:R-DRE-9614423] 14-3-3 proteins bind AKT-phosphorylated FOXO1 - Danio rerio [Reaction:R-DRE-9614562] 14-3-3 proteins bind AKT-phosphorylated FOXO3 - Danio rerio
inferredFrom	[Pathway:R-HSA-9614399] Regulation of localization of FOXO transcription factors - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Regulation of localization of FOXO transcription factors
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-9614399
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9614085] FOXO-mediated transcription
(inferredTo)	[Pathway:R-HSA-9614399] Regulation of localization of FOXO transcription factors

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