Reactome | CDC42 GDIs block activation of CDC42

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10637622
displayName	CDC42 GDIs block activation of CDC42
eventOf	[Pathway:R-DRE-9013148] CDC42 GTPase cycle - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9013158] CDC42 GDIs block activation of CDC42 - Homo sapiens
input	[DefinedSet:R-DRE-9013243] CDC42 GDIs [cytosol] [Complex:R-DRE-9013230] CDC42:GDP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CDC42 GDIs block activation of CDC42
output	[Complex:R-DRE-9013239] CDC42:GDP:CDC42 GDIs [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-9013158
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-9013148] CDC42 GTPase cycle
(inferredTo)	[Reaction:R-HSA-9013158] CDC42 GDIs block activation of CDC42

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