Reactome | RHO GTPase cycle

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RHO GTPase cycle Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649980
displayName	RHO GTPase cycle
eventOf	[Pathway:R-DRE-194315] Signaling by Rho GTPases - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160228] regulation of small GTPase mediated signal transduction
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-8980692] RHOA GTPase cycle - Danio rerio [Pathway:R-DRE-9013026] RHOB GTPase cycle - Danio rerio [Pathway:R-DRE-9013106] RHOC GTPase cycle - Danio rerio [Pathway:R-DRE-9013149] RAC1 GTPase cycle - Danio rerio [Pathway:R-DRE-9013404] RAC2 GTPase cycle - Danio rerio [Pathway:R-DRE-9013423] RAC3 GTPase cycle - Danio rerio [Pathway:R-DRE-9013408] RHOG GTPase cycle - Danio rerio [Pathway:R-DRE-9013148] CDC42 GTPase cycle - Danio rerio [Pathway:R-DRE-9013409] RHOJ GTPase cycle - Danio rerio [Pathway:R-DRE-9013406] RHOQ GTPase cycle - Danio rerio [Pathway:R-DRE-9013420] RHOU GTPase cycle - Danio rerio [Pathway:R-DRE-9013424] RHOV GTPase cycle - Danio rerio [Pathway:R-DRE-9035034] RHOF GTPase cycle - Danio rerio [Pathway:R-DRE-9706574] RHOBTB GTPase Cycle - Danio rerio [Pathway:R-DRE-9013407] RHOH GTPase cycle - Danio rerio [Pathway:R-DRE-9696273] RND1 GTPase cycle - Danio rerio [Pathway:R-DRE-9696270] RND2 GTPase cycle - Danio rerio [Pathway:R-DRE-9696264] RND3 GTPase cycle - Danio rerio
inferredFrom	[Pathway:R-HSA-9012999] RHO GTPase cycle - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	RHO GTPase cycle
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-9012999
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-194315] Signaling by Rho GTPases
(inferredTo)	[Pathway:R-HSA-9012999] RHO GTPase cycle

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