Reactome | RHOA GTPase cycle

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RHOA GTPase cycle Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650382
displayName	RHOA GTPase cycle
eventOf	[Pathway:R-DRE-9012999] RHO GTPase cycle - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-8980691] RHOA GEFs activate RHOA - Danio rerio [Reaction:R-DRE-8981637] RHOA GAPs stimulate RHOA GTPase activity - Danio rerio [Reaction:R-DRE-9012835] GDIs block activation of RHOA - Danio rerio [Reaction:R-DRE-9013009] RHOA binds effectors at the plasma membrane - Danio rerio [BlackBoxEvent:R-DRE-9013006] RHOA:GTP translocates to the ER membrane - Danio rerio [Reaction:R-DRE-9013004] RHOA binds effectors at the ER membrane - Danio rerio
inferredFrom	[Pathway:R-HSA-8980692] RHOA GTPase cycle - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RHOA GTPase cycle
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-8980692
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-9012999] RHO GTPase cycle
(inferredTo)	[Pathway:R-HSA-8980692] RHOA GTPase cycle

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