Reactome | BTK in active Gq-BTK complex is activated

Schema > Reaction > Entries

BTK in active Gq-BTK complex is activated Show undefined attributes

category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10636239
displayName	BTK in active Gq-BTK complex is activated
eventOf	[Pathway:R-DRE-416476] G alpha (q) signalling events - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-8964340] Gq-BTK complex dissociates to Active BTK and Gq - Danio rerio
inferredFrom	[Reaction:R-HSA-8964284] BTK in active Gq-BTK complex is activated - Homo sapiens
input	[Complex:R-DRE-8964296] Active Gq:BTK [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	BTK in active Gq-BTK complex is activated
output	[Complex:R-DRE-8964296] Active Gq:BTK [plasma membrane]
precedingEvent	[Reaction:R-DRE-8964280] Active Gq binds BTK - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8964284
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-416476] G alpha (q) signalling events
(precedingEvent)	[Reaction:R-DRE-8964340] Gq-BTK complex dissociates to Active BTK and Gq
(inferredTo)	[Reaction:R-HSA-8964284] BTK in active Gq-BTK complex is activated

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