Reactome | CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DRE-8952580] NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] - Danio rerio
consumedByEvent	[Reaction:R-DRE-8952639] NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10635751
displayName	CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm]
hasComponent	[Complex:R-DRE-8955650] COMMDs:CCDC22 [nucleoplasm] [Complex:R-DRE-976149] RBX1:CUL4:DDB1:DCAFs [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-8955268] CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] - Homo sapiens
maxDepth	4
name	CRL4 E3 ubiquitin ligase:COMMDs:CCDC22
producedByEvent	[Reaction:R-DRE-8955285] COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-8955268
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-8952639] NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex
(output)	[Reaction:R-DRE-8955285] COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex
(hasComponent)	[Complex:R-DRE-8952580] NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm]
(inferredTo)	[Complex:R-HSA-8955268] CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm]

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