Reactome | DNPH1 hydrolyses dGMP

Schema > Reaction > Entries

DNPH1 hydrolyses dGMP Show undefined attributes

catalystActivity	[CatalystActivity:10635848] 5-hydroxymethyl-dUMP N-hydrolase activity of DNPH1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10635850
displayName	DNPH1 hydrolyses dGMP
eventOf	[Pathway:R-DRE-74259] Purine catabolism - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-74255] Guanine + H2O => Xanthine + NH4+ - Danio rerio
inferredFrom	[Reaction:R-HSA-8953339] DNPH1 hydrolyses dGMP - Homo sapiens
input	[SimpleEntity:R-ALL-109327] dGMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	DNPH1 hydrolyses dGMP dGMP + H2O => 2-deoxy-D-ribose 5-phosphate + guanine
output	[SimpleEntity:R-ALL-8953344] 2DORP [cytosol] [SimpleEntity:R-ALL-83956] Gua [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8953339
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-74259] Purine catabolism
(precedingEvent)	[Reaction:R-DRE-74255] Guanine + H2O => Xanthine + NH4+
(inferredTo)	[Reaction:R-HSA-8953339] DNPH1 hydrolyses dGMP

Cite Us!