Reactome | si:ch1073-205c8.4 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-DRE-8951749] AcM-UBE2M:NEDD8-UBA3:NAE1:NEDD8 [cytosol] - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10608824
displayName	si:ch1073-205c8.4 [cytosol]
endCoordinate	183
hasModifiedResidue	[ModifiedResidue:10608818] N-acetyl-L-methionine at 1 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-8951627] AcM-UBE2M [cytosol] - Homo sapiens
maxDepth	1
name	si:ch1073-205c8.4 AcM-UBE2M A0A0R4IUU4
producedByEvent	[Reaction:R-DRE-8952618] AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex - Danio rerio [Reaction:R-DRE-8952631] AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex - Danio rerio [Reaction:R-DRE-8952626] AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex - Danio rerio [Reaction:R-DRE-4332236] CBL neddylates TGFBR2 - Danio rerio [Reaction:R-DRE-4332236] CBL neddylates TGFBR2 - Danio rerio
referenceEntity	[ReferenceGeneProduct:uniprot:A0A0R4IUU4] UniProt:A0A0R4IUU4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-8951627
startCoordinate	1

(output)	[Reaction:R-DRE-8952618] AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex [Reaction:R-DRE-8952631] AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex [Reaction:R-DRE-8952626] AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex [Reaction:R-DRE-4332236] CBL neddylates TGFBR2
(hasComponent)	[Complex:R-DRE-8951749] AcM-UBE2M:NEDD8-UBA3:NAE1:NEDD8 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-8951627] AcM-UBE2M [cytosol]

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