Reactome | Regulation of PTEN gene transcription

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650356
displayName	Regulation of PTEN gene transcription
eventOf	[Pathway:R-DRE-6807070] PTEN Regulation - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-8943780] SALL4 recruits NuRD to PTEN gene - Danio rerio [Reaction:R-DRE-8944454] mTORC1 phosphorylates MAF1 - Danio rerio [BlackBoxEvent:R-DRE-8944457] MAF1 translocates to the nucleus - Danio rerio
inferredFrom	[Pathway:R-HSA-8943724] Regulation of PTEN gene transcription - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Regulation of PTEN gene transcription
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-8943724
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-6807070] PTEN Regulation
(inferredTo)	[Pathway:R-HSA-8943724] Regulation of PTEN gene transcription

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