Reactome | PTK6 phosphorylates AKT1

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PTK6 phosphorylates AKT1 Show undefined attributes

catalystActivity	[CatalystActivity:10629438] protein tyrosine kinase activity of p-Y342-PTK6:AKT1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10629440
displayName	PTK6 phosphorylates AKT1
eventOf	[Pathway:R-DRE-8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8848758] PTK6 phosphorylates AKT1 - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DRE-8848750] p-Y342-PTK6:AKT1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PTK6 phosphorylates AKT1
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-DRE-8848769] p-Y342-PTK6:p-Y315,Y326-AKT1 [cytosol]
precedingEvent	[Reaction:R-DRE-8848751] PTK6 binds AKT1 - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-8848758
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
(inferredTo)	[Reaction:R-HSA-8848758] PTK6 phosphorylates AKT1

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