Reactome | PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10619506] protein serine/threonine kinase activity of PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-DRE-5693575] DNA-PKcs autophosphorylates - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10619505
displayName	PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
hasComponent	[OtherEntity:R-ALL-75165] DNA double-strand break ends [nucleoplasm] 2 × [Complex:R-DRE-5686711] PRKDC:XRCC5:XRCC6 heterotrimer [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-75907] PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm] - Homo sapiens
maxDepth	4
name	PRKDC:XRCC5:XRCC6:DNA DSB ends
producedByEvent	[Reaction:R-DRE-5693615] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-75907
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-5693575] DNA-PKcs autophosphorylates
(physicalEntity)	[CatalystActivity:10619506] protein serine/threonine kinase activity of PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]
(output)	[Reaction:R-DRE-5693615] Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis
(inferredTo)	[Complex:R-HSA-75907] PRKDC:XRCC5:XRCC6:DNA DSB ends [nucleoplasm]

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