Reactome | Resolution of Abasic Sites (AP sites)

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Resolution of Abasic Sites (AP sites) Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10647668
displayName	Resolution of Abasic Sites (AP sites)
eventOf	[Pathway:R-DRE-73884] Base Excision Repair - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:17139] base-excision repair, gap-filling
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-110357] Displacement of DNA glycosylase by APEX1 - Danio rerio [Reaction:R-DRE-110359] APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site - Danio rerio [Pathway:R-DRE-110381] Resolution of AP sites via the single-nucleotide replacement pathway - Danio rerio [Pathway:R-DRE-5649702] APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway - Danio rerio [Pathway:R-DRE-110373] Resolution of AP sites via the multiple-nucleotide patch replacement pathway - Danio rerio
inferredFrom	[Pathway:R-HSA-73933] Resolution of Abasic Sites (AP sites) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Resolution of Abasic Sites (AP sites)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-73933
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-73884] Base Excision Repair
(inferredTo)	[Pathway:R-HSA-73933] Resolution of Abasic Sites (AP sites)
(hasEncapsulatedEvent)	[Pathway:R-DRE-73929] Base-Excision Repair, AP Site Formation