Reactome | glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP

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glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP Show undefined attributes

catalystActivity	[CatalystActivity:10562164] phosphorylase kinase activity of phosphorylase kinase complex (PHKM) [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10562166
displayName	glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP
eventOf	[Pathway:R-DRE-70221] Glycogen breakdown (glycogenolysis) - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-71541] glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-DRE-71538] PYGM dimer, b form [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP L-seryl-(protein) + ATP => O-phospho-L-seryl-(protein) + ADP + H(+)
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [Complex:R-DRE-71513] PYGM dimer a form [cytosol]
precedingEvent	[Reaction:R-DRE-453338] PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP - Danio rerio
regulatedBy	[PositiveRegulation:R-HSA-2889054] Positive regulation by 'Ca2+ [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-71541
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-70221] Glycogen breakdown (glycogenolysis)
(inferredTo)	[Reaction:R-HSA-71541] glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP

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