Reactome | Proteolytic degradation of ubiquitinated-Cdc25A

Schema > BlackBoxEvent > Entries

Proteolytic degradation of ubiquitinated-Cdc25A Show undefined attributes

catalystActivity	[CatalystActivity:10560135] endopeptidase activity of 26S proteasome [nucleoplasm]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10560900
displayName	Proteolytic degradation of ubiquitinated-Cdc25A
eventOf	[Pathway:R-DRE-69601] Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-69600] Proteolytic degradation of ubiquitinated-Cdc25A - Homo sapiens
input	[EntityWithAccessionedSequence:R-DRE-9944027] phospho-cdc25b [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Proteolytic degradation of ubiquitinated-Cdc25A
output	3 × [DefinedSet:R-DRE-68524] Ub [nucleoplasm]
precedingEvent	[Reaction:R-DRE-69598] Ubiquitination of phosphorylated CDC25A - Danio rerio
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68323] Danio rerio
stId	R-DRE-69600
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-69601] Ubiquitin-Mediated Degradation of Phosphorylated Cdc25A
(inferredTo)	[BlackBoxEvent:R-HSA-69600] Proteolytic degradation of ubiquitinated-Cdc25A

Cite Us!