Reactome | DNA polymerase alpha:primase [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10560479] DNA-directed DNA polymerase activity of DNA polymerase alpha:primase [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DRE-68510] DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] - Danio rerio [Complex:R-DRE-9668602] POLA:primase:G-strand extended telomere end [nucleoplasm] - Danio rerio [Complex:R-DRE-68423] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] - Danio rerio
consumedByEvent	[Reaction:R-DRE-68914] DNA polymerase alpha:primase binds at the origin - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10560157
displayName	DNA polymerase alpha:primase [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-DRE-68487] pola1 [nucleoplasm] [EntityWithAccessionedSequence:R-DRE-68493] pola2 [nucleoplasm] [Complex:R-DRE-9668812] PRIM1:PRIM2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-68507] DNA polymerase alpha:primase [nucleoplasm] - Homo sapiens
maxDepth	3
name	DNA polymerase alpha:primase
producedByEvent	[Reaction:R-DRE-113504] Detection of damage during initiation of DNA synthesis in S-phase - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-68507
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-DRE-113504] Detection of damage during initiation of DNA synthesis in S-phase
(physicalEntity)	[CatalystActivity:10560479] DNA-directed DNA polymerase activity of DNA polymerase alpha:primase [nucleoplasm]
(activeUnit)	[CatalystActivity:10560182] DNA-directed RNA polymerase activity of DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] [CatalystActivity:10571773] DNA-directed DNA polymerase activity of RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm]
(input)	[Reaction:R-DRE-68914] DNA polymerase alpha:primase binds at the origin
(hasComponent)	[Complex:R-DRE-68510] DNA polymerase alpha:primase:DNA polymerase alpha:origin complex [nucleoplasm] [Complex:R-DRE-68423] RNA primer:origin duplex:DNA polymerase alpha:primase complex [nucleoplasm] [Complex:R-DRE-9668602] POLA:primase:G-strand extended telomere end [nucleoplasm] [Complex:R-DRE-174434] RNA primer:G-strand extended telomere end:POLA:primase [nucleoplasm]
(inferredTo)	[Complex:R-HSA-68507] DNA polymerase alpha:primase [nucleoplasm]

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