Reactome | RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12)

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RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10628198
displayName	RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12)
eventOf	[Pathway:R-DRE-6807505] RNA polymerase II transcribes snRNA genes - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-6810233] CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter - Danio rerio
inferredFrom	[Reaction:R-HSA-6810238] RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) - Homo sapiens
input	[Complex:R-DRE-6810225] Initiation factors:CDK7:snRNA gene [nucleoplasm] [Complex:R-DRE-113401] RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) RNA polymerase II binds TBP:TFIIB:TFIIA:TFIIE:TFIIF:snTAFc:CDK7:SNAPc:POU2F1:ZNF143:RNU1-1,RNU2-1 gene
output	[Complex:R-DRE-6810219] RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm]
precedingEvent	[Reaction:R-DRE-6810234] General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-6810238
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-6807505] RNA polymerase II transcribes snRNA genes
(precedingEvent)	[Reaction:R-DRE-6810233] CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter
(inferredTo)	[Reaction:R-HSA-6810238] RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12)

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