Reactome | TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain

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TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10650162
displayName	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
eventOf	[Pathway:R-DRE-6791312] TP53 Regulates Transcription of Cell Cycle Genes - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-6798044] BTG2 binds CCR4-NOT complex - Danio rerio [Reaction:R-DRE-6801666] PLK2 phosphorylates CENPJ - Danio rerio [Reaction:R-DRE-6801675] PLK2 phosphorylates NPM1 - Danio rerio [Reaction:R-DRE-6802973] PLK3 phosphorylates CDC25C - Danio rerio
inferredFrom	[Pathway:R-HSA-6804115] TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-6804115
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-6791312] TP53 Regulates Transcription of Cell Cycle Genes
(inferredTo)	[Pathway:R-HSA-6804115] TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain

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