Reactome | nthl1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DRE-110183] NTHL1:FapyA-dsDNA [nucleoplasm] - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10566427
displayName	nthl1 [nucleoplasm]
endCoordinate	304
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-60537] NTHL1 [nucleoplasm] - Homo sapiens
maxDepth	1
name	nthl1 NTHL1 F1QBP9
producedByEvent	[Reaction:R-DRE-110352] Displacement of NTHL1 glycosylase by APEX1 at the AP site - Danio rerio
referenceEntity	[ReferenceGeneProduct:uniprot:F1QBP9] UniProt:F1QBP9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68323] Danio rerio
stId	R-DRE-60537
startCoordinate	23

(output)	[Reaction:R-DRE-110352] Displacement of NTHL1 glycosylase by APEX1 at the AP site
(activeUnit)	[CatalystActivity:10566502] oxidized purine nucleobase lesion DNA N-glycosylase activity of NTHL1:FapyA-dsDNA [nucleoplasm] [CatalystActivity:10566488] oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity of NTHL1:Cg-dsDNA [nucleoplasm] [CatalystActivity:10566495] oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity of NTHL1:DHU-dsDNA [nucleoplasm] [CatalystActivity:10566481] oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity of NTHL1:Tg-dsDNA [nucleoplasm]
(hasComponent)	[Complex:R-DRE-110183] NTHL1:FapyA-dsDNA [nucleoplasm] [Complex:R-DRE-110179] NTHL1:Cg-dsDNA [nucleoplasm] [Complex:R-DRE-110181] NTHL1:DHU-dsDNA [nucleoplasm] [Complex:R-DRE-110193] NTHL1:AP-dsDNA [nucleoplasm] [Complex:R-DRE-110177] NTHL1:Tg-dsDNA [nucleoplasm]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-60537] NTHL1 [nucleoplasm]