Reactome | ALDH8A1 oxidises 9cRAL to 9cRA

Schema > Reaction > Entries

ALDH8A1 oxidises 9cRAL to 9cRA Show undefined attributes

catalystActivity	[CatalystActivity:10620038] retinal dehydrogenase (NAD+) activity of ALDH8A1 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10620040
displayName	ALDH8A1 oxidises 9cRAL to 9cRA
eventOf	[Pathway:R-DRE-5365859] RA biosynthesis pathway - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-211923] CYP26C1 4-hydroxylates 9cRA - Danio rerio
inferredFrom	[Reaction:R-HSA-5696101] ALDH8A1 oxidises 9cRAL to 9cRA - Homo sapiens
input	[SimpleEntity:R-ALL-5362565] 9cRAL [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ALDH8A1 oxidises 9cRAL to 9cRA
output	[SimpleEntity:R-ALL-5362520] 9cRA [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5696101
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5365859] RA biosynthesis pathway
(precedingEvent)	[Reaction:R-DRE-211923] CYP26C1 4-hydroxylates 9cRA
(inferredTo)	[Reaction:R-HSA-5696101] ALDH8A1 oxidises 9cRAL to 9cRA

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