Reactome | MAPK1/MAPK3 signaling

Schema > Pathway > Entries

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10647886
displayName	MAPK1/MAPK3 signaling
eventOf	[Pathway:R-DRE-5683057] MAPK family signaling cascades - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DRE-5673001] RAF/MAP kinase cascade - Danio rerio [Pathway:R-DRE-112409] RAF-independent MAPK1/3 activation - Danio rerio
inferredFrom	[Pathway:R-HSA-5684996] MAPK1/MAPK3 signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	5
name	MAPK1/MAPK3 signaling ERK1/ERK2 pathway
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-5684996
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5683057] MAPK family signaling cascades
(hasEncapsulatedEvent)	[Pathway:R-DRE-448424] Interleukin-17 signaling [Pathway:R-DRE-9764265] Regulation of CDH1 Expression and Function
(inferredTo)	[Pathway:R-HSA-5684996] MAPK1/MAPK3 signaling

Cite Us!