Reactome | Activated FMNL3 binds G-actin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10615513
displayName	Activated FMNL3 binds G-actin
eventOf	[Pathway:R-DRE-5663220] RHO GTPases Activate Formins - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5665767] Activated FMNL3 binds G-actin - Homo sapiens
input	2 × [Complex:R-DRE-203080] Profilin:G-actin [cytosol] [Complex:R-DRE-5665759] RHOC:GTP:FMNL3 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Activated FMNL3 binds G-actin
output	[Complex:R-DRE-5665773] RHOC:GTP:FMNL3:G-actin [plasma membrane]
precedingEvent	[Reaction:R-DRE-5665761] FMNL3 binds RHOC:GTP - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5665767
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-5663220] RHO GTPases Activate Formins
(inferredTo)	[Reaction:R-HSA-5665767] Activated FMNL3 binds G-actin

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