Reactome | Activated FGFR1 [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-DRE-5654260] Activated FGFR1:p-8T-FRS2 [plasma membrane] - Danio rerio [Complex:R-DRE-5654155] activated FGFR1:PLCG1 [plasma membrane] - Danio rerio
consumedByEvent	[Reaction:R-DRE-5656064] Activated FGFR1 binds FLRT1,2,3 - Danio rerio [Reaction:R-DRE-5654569] Activated FGFR1 binds FRS2 - Danio rerio [Reaction:R-DRE-5654571] Activated FGFR1 binds FRS3 - Danio rerio [Reaction:R-DRE-5654167] Activated FGFR1 binds PLCG1 - Danio rerio
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10603526
displayName	Activated FGFR1 [plasma membrane]
hasMember	[Complex:R-DRE-190430] Activated FGFR1b homodimer [plasma membrane] - Danio rerio [Complex:R-DRE-190425] Activated FGFR1c homodimer [plasma membrane] - Danio rerio [Complex:R-DRE-500333] Activated FGFR1c bound to FGF23:Klotho [plasma membrane] - Danio rerio
inDisease	false
inferredFrom	[DefinedSet:R-HSA-5654170] Activated FGFR1 [plasma membrane] - Homo sapiens
maxDepth	7
name	Activated FGFR1
producedByEvent	[Reaction:R-DRE-5654165] p-4Y-PLCG1 dissociates from activated FGFR1 - Danio rerio
schemaClass	DefinedSet
species	[Species:68323] Danio rerio
stId	R-DRE-5654170

(hasComponent)	[Complex:R-DRE-5654260] Activated FGFR1:p-8T-FRS2 [plasma membrane] [Complex:R-DRE-5656063] Activated FGFR1:FLRT [plasma membrane] [Complex:R-DRE-5654255] Activated FGFR1:FRS3 [plasma membrane] [Complex:R-DRE-5654258] Activated FGFR1:SHC1 [plasma membrane] [Complex:R-DRE-5654155] activated FGFR1:PLCG1 [plasma membrane] [Complex:R-DRE-5654154] activated FGFR1:p-4Y-PLCG1 [plasma membrane] [Complex:R-DRE-5654261] Activated FGFR1:p-FRS3 [plasma membrane] [Complex:R-DRE-5654273] Activated FGFR1:p-SHC1 [plasma membrane] [Complex:R-DRE-5654176] Activated FGFR1:FRS2 [plasma membrane] [Complex:R-DRE-5654200] Activated FGFR1:p-FRS2 [plasma membrane]
(input)	[Reaction:R-DRE-5656064] Activated FGFR1 binds FLRT1,2,3 [Reaction:R-DRE-5654571] Activated FGFR1 binds FRS3 [Reaction:R-DRE-5654167] Activated FGFR1 binds PLCG1 [Reaction:R-DRE-5654569] Activated FGFR1 binds FRS2
(output)	[Reaction:R-DRE-5654165] p-4Y-PLCG1 dissociates from activated FGFR1
(inferredTo)	[DefinedSet:R-HSA-5654170] Activated FGFR1 [plasma membrane]

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