Reactome | B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac

Schema > Reaction > Entries

B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac Show undefined attributes

catalystActivity	[CatalystActivity:10614790] lactose synthase activity of B4GALT1:LALBA [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10614792
displayName	B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac
eventOf	[Pathway:R-DRE-5653890] Lactose synthesis - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5653878] B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac - Homo sapiens
input	[SimpleEntity:R-ALL-964746] Glc [Golgi lumen] [SimpleEntity:R-ALL-735682] UDP-Gal [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac UDP-alpha-D-galactose + D-glucose => lactose + UDP + H(+) Glc + UDP-Gal => Lac + UDP
output	[SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [SimpleEntity:R-ALL-5653871] Lac [Golgi lumen] [SimpleEntity:R-ALL-205687] UDP [Golgi lumen]
precedingEvent	[Reaction:R-DRE-5653886] B4GALT1 binds LALBA - Danio rerio [Reaction:R-DRE-5653873] SLC2A1 tetramer transports Glc from cytosol to Golgi lumen - Danio rerio
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-5653878
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-5653890] Lactose synthesis
(inferredTo)	[Reaction:R-HSA-5653878] B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac

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