Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
CandidateSet
>
Entries
Histone H3 [nucleoplasm]
Show undefined attributes
Go to Details
candidateOf
[CandidateSet:R-DRE-5229045] MeR27-histone H3, Histone H3 [nucleoplasm] - Danio rerio
[CandidateSet:R-DRE-4568580] Histone H2A, H2B, H3, H4 [nucleoplasm] - Danio rerio
compartment
[Compartment:7660] nucleoplasm
componentOf
[Complex:R-DRE-4657037] Histone H3:H4 tetramer [nucleoplasm] - Danio rerio
[Complex:R-DRE-4657037] Histone H3:H4 tetramer [nucleoplasm] - Danio rerio
[Complex:R-DRE-5225642] RBBP7:Replicative histone H3 [nucleoplasm] - Danio rerio
[Complex:R-DRE-3364032] Nucleosome with H2BK121ub [nucleoplasm] - Danio rerio
[Complex:R-DRE-3364032] Nucleosome with H2BK121ub [nucleoplasm] - Danio rerio
consumedByEvent
[Reaction:R-DRE-3318486] KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 - Danio rerio
[Reaction:R-DRE-5205799] CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) - Danio rerio
[Reaction:R-DRE-5218952] PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) - Danio rerio
[Reaction:R-DRE-4827383] WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) - Danio rerio
[Reaction:R-DRE-5638333] WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) - Danio rerio
[Reaction:R-DRE-5634750] EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) - Danio rerio
[Reaction:R-DRE-5638332] PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) - Danio rerio
[Reaction:R-DRE-5159245] SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) - Danio rerio
[Reaction:R-DRE-5225649] RBBP7 binds histone H3 - Danio rerio
created
[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId
10605600
displayName
Histone H3 [nucleoplasm]
hasCandidate
[EntityWithAccessionedSequence:R-DRE-181914] hist2h3ca1 [nucleoplasm] - Danio rerio
inDisease
false
inferredFrom
[CandidateSet:R-HSA-3364024] Histone H3 [nucleoplasm] - Homo sapiens
[CandidateSet:R-HSA-4657030] Histone H3 [nucleoplasm] - Homo sapiens
maxDepth
2
name
Histone H3
Replicative histone H3
Replication-dependent histone H3
HIST1H3A,HIST2H3A
producedByEvent
[Reaction:R-DRE-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 - Danio rerio
[Reaction:R-DRE-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 - Danio rerio
[Reaction:R-DRE-3214912] KDM1A, KDM1B demethylate MeK5-histone H3 - Danio rerio
[Reaction:R-DRE-4754176] JMJD6 demethylates MeR3-histone H3 - Danio rerio
schemaClass
CandidateSet
species
[Species:68323] Danio rerio
stId
R-DRE-4657030
Referrals
(hasCandidate)
[CandidateSet:R-DRE-4568580] Histone H2A, H2B, H3, H4 [nucleoplasm]
[CandidateSet:R-DRE-5229045] MeR27-histone H3, Histone H3 [nucleoplasm]
[CandidateSet:R-DRE-5229039] MeR18-histone H3, Histone H3 [nucleoplasm]
[CandidateSet:R-DRE-5244527] MeR3-histone H3, Histone H3 [nucleoplasm]
(input)
[Reaction:R-DRE-3318486] KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3
[Reaction:R-DRE-5225649] RBBP7 binds histone H3
[Reaction:R-DRE-5205799] CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8)
[Reaction:R-DRE-5218952] PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2)
[Reaction:R-DRE-4827383] WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36)
[Reaction:R-DRE-5638333] WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27)
[Reaction:R-DRE-5634750] EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9)
[Reaction:R-DRE-5638332] PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27)
[Reaction:R-DRE-5159245] SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4)
(hasComponent)
[Complex:R-DRE-5225642] RBBP7:Replicative histone H3 [nucleoplasm]
[Complex:R-DRE-4657037] Histone H3:H4 tetramer [nucleoplasm]
[Complex:R-DRE-3364032] Nucleosome with H2BK121ub [nucleoplasm]
(output)
[Reaction:R-DRE-4722133] KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3
[Reaction:R-DRE-4724284] KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3
[Reaction:R-DRE-3214912] KDM1A, KDM1B demethylate MeK5-histone H3
[Reaction:R-DRE-4754176] JMJD6 demethylates MeR3-histone H3
(inferredTo)
[CandidateSet:R-HSA-4657030] Histone H3 [nucleoplasm]
[CandidateSet:R-HSA-3364024] Histone H3 [nucleoplasm]
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text