Reactome | mRNA decay by 5' to 3' exoribonuclease

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10649138
displayName	mRNA decay by 5' to 3' exoribonuclease
eventOf	[Pathway:R-DRE-429914] Deadenylation-dependent mRNA decay - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:22759] nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DRE-429978] Lsm1-7 Complex binds deadenylated mRNA - Danio rerio [Reaction:R-DRE-429860] DCP1-DCP2 complex decaps mRNA - Danio rerio
inferredFrom	[Pathway:R-HSA-430039] mRNA decay by 5' to 3' exoribonuclease - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	mRNA decay by 5' to 3' exoribonuclease
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-430039
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-429914] Deadenylation-dependent mRNA decay
(inferredTo)	[Pathway:R-HSA-430039] mRNA decay by 5' to 3' exoribonuclease

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