Reactome | SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region

Schema > Reaction > Entries

SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region Show undefined attributes

catalystActivity	[CatalystActivity:10584834] potassium:chloride symporter activity of SLC12A4,5,6,7 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10584836
displayName	SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region
eventOf	[Pathway:R-DRE-426117] Cation-coupled Chloride cotransporters - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-426155] SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region - Homo sapiens
input	[SimpleEntity:R-ALL-352022] Cl- [cytosol] [SimpleEntity:R-ALL-29804] K+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region K+/Cl- cotransport
output	[SimpleEntity:R-ALL-188972] Cl- [extracellular region] [SimpleEntity:R-ALL-74126] K+ [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-426155
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-426117] Cation-coupled Chloride cotransporters
(inferredTo)	[Reaction:R-HSA-426155] SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region

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